Which step should be performed first when setting up a bag of fluids for an IV administration?

The first step in setting up a bag of fluids for IV administration is to check the bag for clarity. This is crucial because it ensures that the fluid is clear of any contaminants, particulates, or discoloration that could indicate contamination or spoilage. Administering fluids that are not clear could pose serious risks to the patient, such as infections or adverse reactions.

This initial step helps to maintain the safety and quality of the fluid therapy. Only after confirming that the bag is safe for use should the subsequent steps be performed, which involve preparing the administration set and ensuring proper aseptic technique during the process. Checking clarity is fundamental and cannot be skipped, as it directly impacts patient safety.