Which condition is a potential long-term side effect of corticosteroid use?

Corticosteroids are a class of anti-inflammatory drugs commonly prescribed for various conditions, including allergies, autoimmune diseases, and inflammation. While they can be highly effective, long-term use of corticosteroids is associated with several potential side effects, one of which is the development of gastric ulcers.

Corticosteroids can inhibit the production of certain protective factors in the gastric lining, making it more susceptible to damage from gastric acids. This can result in the formation of ulcers in the stomach, which can lead to discomfort, bleeding, and other gastrointestinal complications.

Understanding this mechanism is crucial for anyone involved in veterinary pharmacology, as it underscores the importance of monitoring patients on long-term corticosteroid therapy for signs of gastrointestinal distress and taking preventive measures, such as recommending concurrent use of gastroprotectants when appropriate.