What is the primary action of ACE inhibitors in the body?

Prepare for the Penn Foster Veterinary Pharmacology Exam. Get ready for your exam with interactive flashcards and multiple-choice questions. Each question comes with hints and explanations to help you succeed!

The primary action of ACE (Angiotensin-Converting Enzyme) inhibitors in the body is to lower blood pressure. These medications work by inhibiting the enzyme that converts angiotensin I to angiotensin II, a potent vasoconstrictor. By reducing the production of angiotensin II, ACE inhibitors promote vasodilation, which leads to a decrease in vascular resistance and, consequently, a lowering of blood pressure.

Additionally, ACE inhibitors help to decrease the secretion of aldosterone, leading to less sodium and water reabsorption in the kidneys. This further contributes to lowering blood pressure, as it reduces the volume of blood circulating in the vessels. Overall, the effect of ACE inhibitors is primarily focused on managing hypertension and improving cardiovascular outcomes in patients with heart failure or those at high risk for heart disease.

Other choices do not accurately reflect the main action of ACE inhibitors. While reducing heart rate may occur indirectly due to the overall decrease in blood pressure, it is not the primary mechanism. Decreasing cardiac preload is an effect seen with some diuretics and vasodilators but is not the direct action of ACE inhibitors. Increasing oxygen delivery is more related to medications that enhance blood flow or improve cardiac output rather than the specific actions of ACE

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