What is a potential side effect of using BAL for arsenic poisoning?

The use of British Anti-Lewisite (BAL), or dimercaprol, in the treatment of arsenic poisoning is associated with several potential side effects, and one significant concern is the risk of kidney failure. BAL is a chelating agent that binds to heavy metals like arsenic and facilitates their excretion via the kidneys. However, the process of chelation can put a strain on renal function, especially in individuals with existing kidney issues or in cases of high doses.

When BAL mobilizes the arsenic from its storage sites within the body, the kidneys are responsible for filtering and excreting the resultant complex. This increased workload can lead to nephrotoxicity, particularly if the patient is already compromised or if the treatment is prolonged. Therefore, potential kidney damage is a serious risk and is a well-recognized side effect that must be monitored during treatment.

While other options, such as respiratory distress, seizures, or hepatic toxicity, can occur with various treatments or as manifestations of poisoning itself, the direct link between BAL's mechanism of action and renal stress highlights the significance of kidney function as a potential side effect when using this antidote for arsenic poisoning.