What is a notable side effect of long-term corticosteroid therapy related to skin health?

Long-term corticosteroid therapy is known to lead to a variety of side effects, particularly concerning skin health. One notable side effect is the thinning of the skin, also referred to as skin atrophy. Corticosteroids work by suppressing inflammation and the immune response, which can affect the structural integrity of the skin. Over time, this suppression can lead to a decrease in collagen production and skin elasticity, resulting in a more fragile and thinner skin layer.

This thinning increases the risk of bruising, tearing, and other injuries to the skin. It may also result in a more translucent appearance, allowing underlying blood vessels to become more visible. Understanding this side effect is important for those managing patients on corticosteroids, as it can inform strategies for skin care and monitoring. Additionally, these changes may lead to increased sensitivity and a higher risk of skin infections, making vigilance necessary in long-term corticosteroid therapy.