How can corticosteroid therapy be adjusted to prevent complications?

Corticosteroid therapy can lead to various complications if not managed properly, particularly when used long-term. One of the key considerations in adjusting corticosteroid therapy to minimize such risks is to taper the dosage gradually. This process allows the body's own adrenal glands time to resume their normal function, which can be suppressed due to prolonged corticosteroid use.

When corticosteroids are administered at high doses over an extended period, the body can become reliant on these external steroids, leading to adrenal insufficiency when the medication is suddenly discontinued. Gradually tapering the dose helps to prevent withdrawal symptoms and allows the adrenal glands to regain their normal production of hormones. This method mitigates the risk of complications such as Cushing's syndrome, which can occur with abrupt cessation of corticosteroid therapy.

Continuously using high doses or failing to schedule doses properly can exacerbate issues associated with corticosteroid use, further highlighting the importance of a careful and gradual tapering strategy.