Cushing's syndrome results from an excess of which hormone?

Cushing's syndrome is specifically caused by an excess production of cortisol, which is a steroid hormone produced by the adrenal glands. Cortisol plays a significant role in various bodily functions, including the regulation of metabolism, immune response, and the body's stress response. When there is an overproduction of cortisol, it can lead to the symptoms associated with Cushing's syndrome, such as weight gain, thinning skin, and high blood pressure.

Understanding the role of cortisol is crucial for recognizing how it affects the body. Increased cortisol levels can occur due to various factors, including tumors on the adrenal glands or pituitary gland, which stimulate cortisol release. This makes cortisol the primary hormone involved in Cushing's syndrome, distinguishing it from other hormones such as adrenaline, aldosterone, or thyroxine, which are linked to different physiological processes or conditions.