By which method is acetylcysteine administered for pulmonary uses?

Acetylcysteine is primarily administered for pulmonary uses through nebulization. This method allows the medication to be delivered directly to the lungs, where it can effectively act as a mucolytic agent. By breaking down mucus, acetylcysteine helps to thin and loosen secretions in the airways, making it easier for patients to clear mucus from their respiratory tract. This route of administration is particularly beneficial in situations like chronic obstructive pulmonary disease (COPD), cystic fibrosis, and other respiratory conditions where mucus accumulation is a problem.

In contrast, while acetylcysteine can also be given orally or intravenously for other medical indications, such as treating acetaminophen toxicity, these methods do not effectively target the pulmonary system for the purpose of mucus management. Topical administration is not applicable for acetylcysteine, as it is not designed to be used in this manner for respiratory issues. Thus, nebulization is the optimal method for utilizing acetylcysteine in pulmonary applications.